GAZA CITY, GAZA STRIP • The Palestinian death toll from last weekend’s fighting between Israel and Gaza militants rose to 48 Thursday after an 11-year-old girl and a man died from wounds they suffered during the worst cross-border violence in over a year.

Meanwhile, two wounded Gaza children, ages 8 and 14, were fighting for their lives in a Jerusalem hospital. In all, more than 300 Palestinians were wounded over the weekend when Israel struck Islamic Jihad targets across Gaza and the militant group fired hundreds of rockets at Israel.

The death of 11-year-old Layan al-Shaer at Mukassed Hospital in an Arab neighborhood of Jerusalem brought to 17 the number of children killed in the fighting.

Israel said it launched the initial wave of airstrikes, which killed an Islamic Jihad commander, in response to an imminent threat from the militant group, days after Israeli troops arrested one of its leaders in the occupied West Bank.